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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB86351.1PFAM: Xanthine/uracil/vitamin C permease; KEGG: dac:Daci_5908 xanthine/uracil/vitamin C permease. (451 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.929
AEB86353.1
TIGRFAM: Xanthine dehydrogenase, molybdopterin binding subunit; KEGG: vap:Vapar_3906 xanthine dehydrogenase, molybdopterin binding subunit; PFAM: Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead.
       0.814
AEB86354.1
TIGRFAM: Xanthine dehydrogenase, small subunit; KEGG: dac:Daci_5910 xanthine dehydrogenase small subunit; PFAM: Molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding; CO dehydrogenase flavoprotein, C-terminal.
       0.796
AEB86350.1
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
       0.790
AEB86352.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: vap:Vapar_3905 transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
     
 0.783
AEB82517.1
KEGG: ajs:Ajs_0048 uracil-xanthine permease; TIGRFAM: Xanthine/uracil permease; PFAM: Xanthine/uracil/vitamin C permease.
 
  
 0.671
AEB85279.1
Xanthine permease; KEGG: ctt:CtCNB1_3177 uracil-xanthine permease; TIGRFAM: Xanthine permease; Xanthine/uracil permease; PFAM: Xanthine/uracil/vitamin C permease.
 
  
 0.615
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.614
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.601
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.599
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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