Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB86392.1KEGG: dia:Dtpsy_2994 cobalamin synthesis protein P47K; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal; SMART: Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal. (356 aa)    
Predicted Functional Partners:
dksA
Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
  
  
 0.885
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
 
 
 0.867
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.820
rpmB
TIGRFAM: Ribosomal protein L28; HAMAP: Ribosomal protein L28; KEGG: ctt:CtCNB1_0883 ribosomal protein L28; PFAM: Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.722
AEB85974.1
Cobaltochelatase; KEGG: dia:Dtpsy_2685 cobaltochelatase; PFAM: CobN/magnesium chelatase.
 
  
 0.688
AEB83468.1
KEGG: dia:Dtpsy_2782 transcriptional regulator, TraR/DksA family.
  
  
 0.668
rpmG
KEGG: dia:Dtpsy_2723 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; PFAM: Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.597
AEB86393.1
KEGG: gpb:HDN1F_32180 hypothetical protein.
       0.551
AEB85015.1
KEGG: dia:Dtpsy_1495 ribosomal protein L31; TIGRFAM: Ribosomal protein L31; PFAM: Ribosomal protein L31; Belongs to the bacterial ribosomal protein bL31 family.
  
  
 0.524
AEB85339.1
KEGG: reu:Reut_C6238 regulatory protein, MerR; PFAM: Cobalamin (vitamin B12)-binding; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR.
  
  
 0.497
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.