close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB86452.1KEGG: rpf:Rpic12D_0449 SSS sodium solute transporter superfamily; TIGRFAM: Sodium/solute symporter, subgroup; PFAM: Sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (578 aa)    
Predicted Functional Partners:
AEB86451.1
PFAM: Protein of unknown function DUF485; KEGG: dac:Daci_5956 hypothetical protein.
 
  
 0.989
AEB86454.1
Cyclic nucleotide-binding protein; KEGG: dac:Daci_5960 CBS domain-containing protein; PFAM: Domain of unknown function DUF294, nucleotidyltransferase putative; Cystathionine beta-synthase, core; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: Cystathionine beta-synthase, core; Cyclic nucleotide-binding domain.
 
  
 0.909
AEB86453.1
KEGG: pna:Pnap_0481 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease.
 
    0.807
AEB82520.1
TIGRFAM: Acetoacetyl-CoA synthase; KEGG: dia:Dtpsy_0074 acetoacetyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.440
AEB83909.1
Acetate--CoA ligase; KEGG: bbr:BB0615 AMP-binding enzyme; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.440
AEB85215.1
TIGRFAM: Propionate--CoA ligase; KEGG: dia:Dtpsy_1825 propionyl-CoA synthetase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.440
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.440
AEB86850.1
Acetate--CoA ligase; KEGG: bur:Bcep18194_C7155 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase.
  
  
 0.440
AEB86954.1
Acetate--CoA ligase; KEGG: gka:GK2759 acetyl-CoA synthetase (acetate-CoA ligase); PFAM: AMP-dependent synthetase/ligase.
  
  
 0.440
AEB86450.1
PFAM: General substrate transporter; KEGG: ajs:Ajs_3752 major facilitator superfamily transporter.
       0.412
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (22%) [HD]