STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEB86453.1KEGG: pna:Pnap_0481 DNA polymerase III subunit epsilon; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease. (221 aa)    
Predicted Functional Partners:
AEB86454.1
Cyclic nucleotide-binding protein; KEGG: dac:Daci_5960 CBS domain-containing protein; PFAM: Domain of unknown function DUF294, nucleotidyltransferase putative; Cystathionine beta-synthase, core; Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding; SMART: Cystathionine beta-synthase, core; Cyclic nucleotide-binding domain.
 
    0.987
AEB82442.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.972
AEB85365.1
DNA polymerase III, alpha subunit; SMART: Polymerase/histidinol phosphatase, N-terminal; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: dia:Dtpsy_1898 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type.
  
 0.970
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.969
AEB86766.1
KEGG: dia:Dtpsy_3264 DNA polymerase III subunit delta; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.
    
 0.947
AEB82462.1
PFAM: Exonuclease, RNase T/DNA polymerase III; KEGG: ajs:Ajs_4160 DNA polymerase III, epsilon subunit; SMART: Exonuclease.
  
  
  0.936
AEB84729.1
PFAM: DNA polymerase III chi subunit, HolC; KEGG: ajs:Ajs_1922 DNA polymerase III chi subunit, HolC.
   
 0.926
AEB85536.1
KEGG: ajs:Ajs_1718 DNA-directed DNA polymerase.
   
 0.924
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
  
  0.915
AEB86451.1
PFAM: Protein of unknown function DUF485; KEGG: dac:Daci_5956 hypothetical protein.
 
    0.838
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.