Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEB86738.1RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (517 aa)    
Predicted Functional Partners:
AEB86164.1
KEGG: dia:Dtpsy_2940 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver domain; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver domain; ATPase, AAA+ type, core.
 
  
 0.960
AEB86165.1
KEGG: dia:Dtpsy_2939 histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain.
 
  
 0.924
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.883
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.869
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.855
AEB82558.1
Sigma54 specific transcriptional regulator, Fis family; KEGG: dia:Dtpsy_0110 anaerobic nitric oxide reductase transcription regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core.
 
   
 0.848
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.835
AEB86737.1
KEGG: ajs:Ajs_0349 hypothetical protein.
  
   0.824
AEB84885.1
Sigma54 specific transcriptional regulator with PAS/PAC sensor, Fis family; KEGG: azo:azo3875 sigma-54-dependent transcriptional regulator; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; PAS.
 
  
 0.821
AEB85751.1
KEGG: tmz:Tmz1t_3466 GAF modulated sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; GAF; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core.
 
  
 0.819
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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