Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEB86804.1Xaa-Pro aminopeptidase; KEGG: dia:Dtpsy_3306 peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; PFAM: Peptidase M24, structural domain; Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal. (460 aa)    
Predicted Functional Partners:
AEB86803.1
TIGRFAM: Pyruvate kinase; KEGG: dia:Dtpsy_3305 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; Belongs to the pyruvate kinase family.
  
  
 0.667
AEB85771.1
KEGG: dia:Dtpsy_2249 aminopeptidase N; TIGRFAM: Peptidase M1, alanyl aminopeptidase; PFAM: Peptidase M1, membrane alanine aminopeptidase, N-terminal.
  
 
 0.617
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.591
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 
 0.586
nudJ
PFAM: NUDIX hydrolase domain; KEGG: dia:Dtpsy_3425 NUDIX hydrolase; Belongs to the Nudix hydrolase family. NudJ subfamily.
 
   
 0.554
pepA
Peptidase M17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 
 0.534
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.525
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.514
AEB86808.1
Thiolase domain-containing protein; PFAM: Thiolase, C-terminal; KEGG: rme:Rmet_5111 thiolase.
   
 
 0.512
AEB86812.1
PFAM: Nucleotidyl transferase; KEGG: ajs:Ajs_3958 nucleotidyl transferase.
       0.509
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.