Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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speE-2Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (517 aa)    
Predicted Functional Partners:
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
  
  0.977
AEB86985.1
PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; KEGG: ajs:Ajs_4093 twin-arginine translocation pathway signal.
 
     0.946
AEB86987.1
PFAM: Protein of unknown function DUF350; KEGG: dia:Dtpsy_3447 protein of unknown function DUF350.
 
     0.945
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
 
0.935
AEB86988.1
KEGG: dia:Dtpsy_3448 putative transmembrane protein.
 
     0.924
AEB86797.1
TIGRFAM: MTA/SAH nucleosidase; KEGG: dia:Dtpsy_3298 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; PFAM: Nucleoside phosphorylase domain.
     
 0.904
AEB84812.1
KEGG: dia:Dtpsy_1679 protein of unknown function DUF152; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; PFAM: Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.903
AEB86989.1
PFAM: Band 7 protein; KEGG: ajs:Ajs_4099 putative transmembrane protein.
 
     0.869
AEB86984.1
Hypothetical protein.
       0.475
Your Current Organism:
Alicycliphilus denitrificans
NCBI taxonomy Id: 596154
Other names: A. denitrificans K601, Alicycliphilus denitrificans DSM 14773, Alicycliphilus denitrificans K601, Alicycliphilus denitrificans str. K601, Alicycliphilus denitrificans strain K601, Pseudomonas sp. K601, beta proteobacterium K601
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