node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFM65197.1 | EFM65204.1 | HMPREF0634_0949 | HMPREF0634_0948 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.911 |
EFM65197.1 | EFM65205.1 | HMPREF0634_0949 | HMPREF0634_0950 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | R3H domain protein; Identified by match to protein family HMM PF01424. | 0.932 |
EFM65197.1 | ffh | HMPREF0634_0949 | HMPREF0634_0977 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.947 |
EFM65197.1 | ftsY | HMPREF0634_0949 | HMPREF0634_0663 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.928 |
EFM65197.1 | rnpA | HMPREF0634_0949 | HMPREF0634_0947 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.937 |
EFM65197.1 | secA-2 | HMPREF0634_0949 | HMPREF0634_0711 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.938 |
EFM65197.1 | secE | HMPREF0634_0949 | HMPREF0634_0738 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.970 |
EFM65197.1 | secG | HMPREF0634_0949 | HMPREF0634_1042 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.977 |
EFM65197.1 | secY | HMPREF0634_0949 | HMPREF0634_0086 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.988 |
EFM65197.1 | yajC | HMPREF0634_0949 | HMPREF0634_0647 | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | Preprotein translocase, YajC subunit; Identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739. | 0.925 |
EFM65204.1 | EFM65197.1 | HMPREF0634_0948 | HMPREF0634_0949 | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.911 |
EFM65204.1 | EFM65205.1 | HMPREF0634_0948 | HMPREF0634_0950 | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | R3H domain protein; Identified by match to protein family HMM PF01424. | 0.832 |
EFM65204.1 | rnpA | HMPREF0634_0948 | HMPREF0634_0947 | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.978 |
EFM65204.1 | secE | HMPREF0634_0948 | HMPREF0634_0738 | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.739 |
EFM65204.1 | secG | HMPREF0634_0948 | HMPREF0634_1042 | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.451 |
EFM65205.1 | EFM65197.1 | HMPREF0634_0950 | HMPREF0634_0949 | R3H domain protein; Identified by match to protein family HMM PF01424. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.932 |
EFM65205.1 | EFM65204.1 | HMPREF0634_0950 | HMPREF0634_0948 | R3H domain protein; Identified by match to protein family HMM PF01424. | Conserved hypothetical protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.832 |
EFM65205.1 | rnpA | HMPREF0634_0950 | HMPREF0634_0947 | R3H domain protein; Identified by match to protein family HMM PF01424. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.870 |
ffh | EFM65197.1 | HMPREF0634_0977 | HMPREF0634_0949 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Membrane protein insertase, YidC/Oxa1 family; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592. | 0.947 |
ffh | ftsY | HMPREF0634_0977 | HMPREF0634_0663 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.997 |