STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoD-2Sigma-70, region 4; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (286 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.921
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.899
EEV19923.1
Putative DNA primase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01807; match to protein family HMM PF08275.
 
  
 0.865
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
 0.859
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.856
EEV19442.1
RNA polymerases K / 14 to 18 kDa subunit; Identified by match to protein family HMM PF01192.
   
 
 0.839
EEV21439.1
Identified by match to protein family HMM PF02559.
   
 
 0.828
EEV19924.1
Toprim domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01751.
 
  
 0.827
EEV19300.1
Transcriptional regulator, effector binding domain protein; Identified by match to protein family HMM PF00165; match to protein family HMM PF06445.
    
 
 0.811
EEV20521.1
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
  
 
 0.797
Your Current Organism:
Treponema vincentii
NCBI taxonomy Id: 596324
Other names: T. vincentii ATCC 35580, Treponema vincentii ATCC 35580, Treponema vincentii str. ATCC 35580, Treponema vincentii strain ATCC 35580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.