node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEV19289.1 | EEV20956.1 | TREVI0001_0361 | TREVI0001_0952 | Pentapeptide repeat protein; Identified by match to protein family HMM PF00805. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.437 |
EEV19289.1 | EEV21049.1 | TREVI0001_0361 | TREVI0001_2574 | Pentapeptide repeat protein; Identified by match to protein family HMM PF00805. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | 0.776 |
EEV20956.1 | EEV19289.1 | TREVI0001_0952 | TREVI0001_0361 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pentapeptide repeat protein; Identified by match to protein family HMM PF00805. | 0.437 |
EEV20956.1 | EEV21049.1 | TREVI0001_0952 | TREVI0001_2574 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | 0.653 |
EEV20956.1 | EEV21053.1 | TREVI0001_0952 | TREVI0001_2578 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | SNF2 family N-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434. | 0.575 |
EEV20956.1 | EEV21116.1 | TREVI0001_0952 | TREVI0001_1475 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein. | 0.437 |
EEV20956.1 | dnaN | TREVI0001_0952 | TREVI0001_1741 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.907 |
EEV20956.1 | gyrA | TREVI0001_0952 | TREVI0001_1193 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.546 |
EEV20956.1 | gyrA-2 | TREVI0001_0952 | TREVI0001_1889 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA gyrase/topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | 0.546 |
EEV20956.1 | metG | TREVI0001_0952 | TREVI0001_0758 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.786 |
EEV20956.1 | polA | TREVI0001_0952 | TREVI0001_1134 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.960 |
EEV21049.1 | EEV19289.1 | TREVI0001_2574 | TREVI0001_0361 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Pentapeptide repeat protein; Identified by match to protein family HMM PF00805. | 0.776 |
EEV21049.1 | EEV20956.1 | TREVI0001_2574 | TREVI0001_0952 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.653 |
EEV21049.1 | EEV21053.1 | TREVI0001_2574 | TREVI0001_2578 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | SNF2 family N-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04434. | 0.638 |
EEV21049.1 | EEV21116.1 | TREVI0001_2574 | TREVI0001_1475 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | Hypothetical protein. | 0.776 |
EEV21049.1 | dnaN | TREVI0001_2574 | TREVI0001_1741 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.755 |
EEV21049.1 | gyrA | TREVI0001_2574 | TREVI0001_1193 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.987 |
EEV21049.1 | gyrA-2 | TREVI0001_2574 | TREVI0001_1889 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA gyrase/topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521. | 0.990 |
EEV21049.1 | metG | TREVI0001_2574 | TREVI0001_0758 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.624 |
EEV21049.1 | polA | TREVI0001_2574 | TREVI0001_1134 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF02518. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.696 |