STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hydGIron-only hydrogenase maturation rSAM protein HydG; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968. (472 aa)    
Predicted Functional Partners:
hydF
Hydrogenase maturation GTPase HydF; Identified by match to protein family HMM PF01926; match to protein family HMM TIGR00231.
  
 0.976
thiG
Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 0.961
EEK16925.1
4Fe-4S binding domain protein; Identified by match to protein family HMM PF00037; match to protein family HMM PF02906.
 
   
 0.881
thiE
Putative thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.878
hydE
Iron-only hydrogenase maturation rSAM protein HydE; Identified by match to protein family HMM PF04055.
 
  
0.856
thiH
Thiazole biosynthesis protein ThiH; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR02351.
  
  
 
0.815
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
 
  0.747
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.734
EEK16381.1
Hypothetical protein.
  
  
 0.614
EEK16694.1
Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.
  
  
 0.434
Your Current Organism:
Porphyromonas uenonis 603
NCBI taxonomy Id: 596327
Other names: P. uenonis 60-3, Porphyromonas uenonis 60-3, Porphyromonas uenonis str. 60-3, Porphyromonas uenonis strain 60-3
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.