node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F2 | F2RL2 | ENSTGUP00000010918 | ENSTGUP00000004225 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor II thrombin receptor like 2. | 0.952 |
F2 | F2RL3 | ENSTGUP00000010918 | ENSTGUP00000000480 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.995 |
F2 | H0ZG36_TAEGU | ENSTGUP00000010918 | ENSTGUP00000009548 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.750 |
F2 | LOC100231371 | ENSTGUP00000010918 | ENSTGUP00000011835 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.750 |
F2 | PARD3 | ENSTGUP00000010918 | ENSTGUP00000021463 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Par-3 family cell polarity regulator. | 0.900 |
F2RL2 | F2 | ENSTGUP00000004225 | ENSTGUP00000010918 | Coagulation factor II thrombin receptor like 2. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.952 |
F2RL2 | F2RL3 | ENSTGUP00000004225 | ENSTGUP00000000480 | Coagulation factor II thrombin receptor like 2. | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | 0.959 |
F2RL2 | GZMA | ENSTGUP00000004225 | ENSTGUP00000002528 | Coagulation factor II thrombin receptor like 2. | Granzyme A; Belongs to the peptidase S1 family. | 0.908 |
F2RL2 | H0ZG36_TAEGU | ENSTGUP00000004225 | ENSTGUP00000009548 | Coagulation factor II thrombin receptor like 2. | Uncharacterized protein. | 0.908 |
F2RL2 | LOC100224083 | ENSTGUP00000004225 | ENSTGUP00000022154 | Coagulation factor II thrombin receptor like 2. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.908 |
F2RL2 | LOC100225270 | ENSTGUP00000004225 | ENSTGUP00000000549 | Coagulation factor II thrombin receptor like 2. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.908 |
F2RL2 | LOC100231371 | ENSTGUP00000004225 | ENSTGUP00000011835 | Coagulation factor II thrombin receptor like 2. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.908 |
F2RL2 | PARD3 | ENSTGUP00000004225 | ENSTGUP00000021463 | Coagulation factor II thrombin receptor like 2. | Par-3 family cell polarity regulator. | 0.901 |
F2RL3 | F2 | ENSTGUP00000000480 | ENSTGUP00000010918 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.995 |
F2RL3 | F2RL2 | ENSTGUP00000000480 | ENSTGUP00000004225 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | Coagulation factor II thrombin receptor like 2. | 0.959 |
F2RL3 | GNA12 | ENSTGUP00000000480 | ENSTGUP00000018487 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha 12. | 0.624 |
F2RL3 | GNB5 | ENSTGUP00000000480 | ENSTGUP00000006972 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | WD_REPEATS_REGION domain-containing protein. | 0.620 |
F2RL3 | GZMA | ENSTGUP00000000480 | ENSTGUP00000002528 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | Granzyme A; Belongs to the peptidase S1 family. | 0.928 |
F2RL3 | H0ZG36_TAEGU | ENSTGUP00000000480 | ENSTGUP00000009548 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | Uncharacterized protein. | 0.926 |
F2RL3 | LOC100224083 | ENSTGUP00000000480 | ENSTGUP00000022154 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.926 |