STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RDH8-2Uncharacterized protein. (282 aa)    
Predicted Functional Partners:
RDH10
Uncharacterized protein.
  
  
 0.934
LOC100230746
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
0.933
ALDH1A1
Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.925
LOC100226769
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.925
ALDH1A2
Retinal dehydrogenase 2; Converts retinaldehyde to retinoic acid. Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal (By similarity). Has only very low activity with benzaldehyde and acetaldehyde. Displays complete lack of activity with citral. It is responsible for the ability of brain sites to synthesize retinoic acid. Its activity in the high vocal center (HVC) is required for the song of juvenile zebra finches to become stereotyped.
  
 0.925
ALDH1A3
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.925
DHRS3
Dehydrogenase/reductase 3.
  
  
 0.924
ADH5
Alcohol dehydrogenase 5 (class III), chi polypeptide.
   
 
 0.921
LOC100222320
PKS_ER domain-containing protein.
   
 
 0.921
LOC100218703
Alcohol dehydrogenase 1/7.
   
 
 0.921
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.