STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL6Interleukin 6. (221 aa)    
Predicted Functional Partners:
IL6R
Interleukin 6 receptor.
   
 0.989
IL10
Interleukin 10.
   
 
 0.904
STAT3
Signal transducer and activator of transcription.
   
 0.861
EBI3
Interleukin-27 subunit beta.
   
 0.822
CNTFR
Ciliary neurotrophic factor receptor.
   
 0.822
IL11RA
Uncharacterized protein.
   
 0.822
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
  
 0.818
IL18
Interleukin-18.
     
 0.801
IL1B
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.798
IL6ST
Interleukin 6 signal transducer.
    
 0.791
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.