STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1089 aa)    
Predicted Functional Partners:
CAMK4
Calcium/calmodulin dependent protein kinase IV.
   
  0.903
ARID4B
AT-rich interaction domain 4B.
    
 0.845
ARID4A
ARID domain-containing protein.
    
 0.845
SIN3B
SIN3 transcription regulator family member B.
   
 0.646
SIN3A
SIN3 transcription regulator family member A.
   
 0.646
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.642
WDR73
WD repeat domain 73.
   
 0.563
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.562
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.562
NCOR2
Nuclear receptor corepressor 2.
    
 0.561
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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