STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTRLChymotrypsin like; Belongs to the peptidase S1 family. (262 aa)    
Predicted Functional Partners:
PVALB
Putative parvalbumin variant 3; Belongs to the parvalbumin family.
    
 
 0.700
SUMO1
Small ubiquitin-related modifier.
    
 
 0.681
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
      
 0.677
HIVEP3
Human immunodeficiency virus type I enhancer binding protein 3.
    
 
 0.677
MST1R
Macrophage stimulating 1 receptor.
    
  0.648
MET
MET proto-oncogene, receptor tyrosine kinase.
    
  0.648
CPA1
Carboxypeptidase A1.
 
 
 
 0.630
H0ZG36_TAEGU
Uncharacterized protein.
 
   
 0.578
CPB1
Carboxypeptidase B1.
 
 
 
 0.570
ENSTGUP00000032818
Muscle M-line assembly protein unc-89-like.
    
 0.562
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.