STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1103 aa)    
Predicted Functional Partners:
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
  0.901
CACNB2
Calcium voltage-gated channel auxiliary subunit beta 2.
   
 0.743
CACNB1
Voltage-dependent L-type calcium channel subunit beta-1 isoform X1.
   
 0.743
CACNB4
SH3 domain-containing protein.
   
 0.730
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
   
 0.723
CACNG1
Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
    
 
 0.700
CAMK2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2.
   
 
 0.698
CAMK2B
Protein kinase domain-containing protein.
   
 
 0.697
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.
   
 0.696
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
   
 
 0.658
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.