STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNJ11Potassium voltage-gated channel subfamily J member 11. (401 aa)    
Predicted Functional Partners:
ABCC8
ATP binding cassette subfamily C member 8.
 
 
 0.997
ABCC9
Uncharacterized protein.
 
 
 0.984
KCNJ8
Potassium voltage-gated channel subfamily J member 8.
  
 
 
0.685
RAPGEF4
Rap guanine nucleotide exchange factor 4.
     
 0.670
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
 0.635
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
      
 0.525
XIAP
X-linked inhibitor of apoptosis.
    
 
 0.516
SERGEF
Secretion regulating guanine nucleotide exchange factor.
     
 0.511
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
   
  
 0.488
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.450
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (18%) [HD]