Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP28Rho GTPase activating protein 28. (605 aa)    
Predicted Functional Partners:
ARHGAP18
Rho GTPase activating protein 18.
    
   0.776
XPO1
Exportin 1.
      
 0.658
CRK
Uncharacterized protein.
      
 0.639
GPHN
Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
      
 0.623
ENOX1
Ecto-NOX disulfide-thiol exchanger 1.
      
 0.604
LOC100226244
Uncharacterized protein.
   
 0.597
LYN
Tyrosine-protein kinase.
      
 0.597
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
      
 0.592
GRB2
Putative growth factor receptor-bound protein 2.
      
 0.589
EGFL6
Uncharacterized protein.
      
 0.587
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (10%) [HD]