STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSTGUP00000010433annotation not available (772 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.984
ITSN1
Intersectin 1.
   
 0.869
ITSN1-2
Intersectin 1.
   
 0.869
AP2M1
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.769
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 0.681
EPS15
Uncharacterized protein.
    
 0.681
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
 0.664
LOC115492856
Adaptor related protein complex 2 subunit sigma 1.
    
 0.654
LOC115492856-2
AP-2 complex subunit sigma.
    
 0.654
AP1B1
Adaptor related protein complex 1 subunit beta 1.
    
 0.623
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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