STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (357 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.690
EDN1
Endothelin 1.
   
 
 0.597
AGTR2
Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family.
    
 
0.581
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.576
NTS
Uncharacterized protein.
     
 0.563
NMB
Uncharacterized protein.
     
 0.550
GNA11
G protein subunit alpha 11.
    
 0.505
LOC100230245
Uncharacterized protein.
    
 0.505
TRIO
Trio Rho guanine nucleotide exchange factor.
    
  0.504
KALRN
Uncharacterized protein.
    
  0.504
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.