STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (813 aa)    
Predicted Functional Partners:
GRB2
Putative growth factor receptor-bound protein 2.
   
 0.801
IL1RAP
Uncharacterized protein.
    
 0.643
IL1RAPL2
Interleukin 1 receptor accessory protein like 2.
    
 0.608
LRFN5
Leucine rich repeat and fibronectin type III domain containing 5.
    
 0.562
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
    
 0.540
SLITRK2
SLIT and NTRK like family member 2.
    
 0.523
NTRK2
Tyrosine-protein kinase receptor.
   
 0.521
NTRK3
Tyrosine-protein kinase receptor.
   
 0.521
ENSTGUP00000031473
annotation not available
   
 0.521
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.516
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.