STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE4ANon-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (367 aa)    
Predicted Functional Partners:
NSMCE1
RING-type domain-containing protein.
   
 0.999
SMC5
AAA_15 domain-containing protein.
   
 0.999
SMC6
Structural maintenance of chromosomes 6.
   
 0.998
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.997
ENSTGUP00000019528
annotation not available
   
 0.969
LOC100190649
Taeniopygia guttata necdin-like 2-like (LOC100190649), mRNA.
   
 0.969
SMC3
Structural maintenance of chromosomes protein.
   
 0.922
ENSTGUP00000032703
annotation not available
   
 0.904
PRAM1
hSH3 domain-containing protein.
   
 0.904
SMC1B
Structural maintenance of chromosomes protein.
   
 0.870
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.