STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RECQLATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (661 aa)    
Predicted Functional Partners:
PYROXD1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
     
 0.718
SLCO1A2
Solute carrier organic anion transporter family member.
      
 0.699
EXO1
Exonuclease 1.
    
 
 0.595
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.558
DNA2
Uncharacterized protein.
      
 0.552
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
      
 0.544
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
    
 
 0.538
NOL6
Nucleolar protein 6.
      
 0.534
XRCC6
SAP domain-containing protein.
    
 
 0.530
GUK1
Guanylate kinase 1.
 
  
  0.525
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.