node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGO1 | AGO2 | ENSTGUP00000001697 | ENSTGUP00000013029 | Eukaryotic translation initiation factor 2C. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.867 |
AGO1 | DICER1 | ENSTGUP00000001697 | ENSTGUP00000013036 | Eukaryotic translation initiation factor 2C. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.933 |
AGO1 | ENSTGUP00000020667 | ENSTGUP00000001697 | ENSTGUP00000020667 | Eukaryotic translation initiation factor 2C. | annotation not available | 0.650 |
AGO1 | ENSTGUP00000024832 | ENSTGUP00000001697 | ENSTGUP00000024832 | Eukaryotic translation initiation factor 2C. | annotation not available | 0.650 |
AGO1 | ENSTGUP00000036769 | ENSTGUP00000001697 | ENSTGUP00000036769 | Eukaryotic translation initiation factor 2C. | annotation not available | 0.650 |
AGO1 | STAU1 | ENSTGUP00000001697 | ENSTGUP00000019027 | Eukaryotic translation initiation factor 2C. | Staufen double-stranded RNA binding protein 1. | 0.569 |
AGO1 | TARBP2 | ENSTGUP00000001697 | ENSTGUP00000028687 | Eukaryotic translation initiation factor 2C. | TARBP2 subunit of RISC loading complex. | 0.650 |
AGO2 | AGO1 | ENSTGUP00000013029 | ENSTGUP00000001697 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Eukaryotic translation initiation factor 2C. | 0.867 |
AGO2 | AGO3 | ENSTGUP00000013029 | ENSTGUP00000015372 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | 0.867 |
AGO2 | AGO4 | ENSTGUP00000013029 | ENSTGUP00000025390 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Argonaute RISC component 4; Belongs to the argonaute family. | 0.867 |
AGO2 | DGCR8 | ENSTGUP00000013029 | ENSTGUP00000018761 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DGCR8 microprocessor complex subunit. | 0.573 |
AGO2 | DICER1 | ENSTGUP00000013029 | ENSTGUP00000013036 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.987 |
AGO2 | ENSTGUP00000020667 | ENSTGUP00000013029 | ENSTGUP00000020667 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | annotation not available | 0.706 |
AGO2 | ENSTGUP00000024832 | ENSTGUP00000013029 | ENSTGUP00000024832 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | annotation not available | 0.706 |
AGO2 | ENSTGUP00000036769 | ENSTGUP00000013029 | ENSTGUP00000036769 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | annotation not available | 0.706 |
AGO2 | STAU1 | ENSTGUP00000013029 | ENSTGUP00000019027 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staufen double-stranded RNA binding protein 1. | 0.569 |
AGO2 | TARBP2 | ENSTGUP00000013029 | ENSTGUP00000028687 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | TARBP2 subunit of RISC loading complex. | 0.786 |
AGO3 | AGO2 | ENSTGUP00000015372 | ENSTGUP00000013029 | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.867 |
AGO3 | DICER1 | ENSTGUP00000015372 | ENSTGUP00000013036 | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.933 |
AGO3 | ENSTGUP00000020667 | ENSTGUP00000015372 | ENSTGUP00000020667 | Argonaute RISC catalytic component 3; Belongs to the argonaute family. | annotation not available | 0.650 |