STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2258 aa)    
Predicted Functional Partners:
F2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
    
 0.965
PROS1
Uncharacterized protein.
   
 0.744
PROC
Protein C, inactivator of coagulation factors Va and VIIIa.
    
 0.737
F9
Coagulation factor IX.
   
 0.708
PROZ
Protein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family.
   
 0.708
F7
Coagulation factor VII.
   
 0.708
F10
Uncharacterized protein.
   
 0.708
MCFD2
Multiple coagulation factor deficiency 2.
     
 0.681
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
    
 0.673
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
     
0.655
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
Server load: low (10%) [HD]