STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPC2NPC intracellular cholesterol transporter 2. (150 aa)    
Predicted Functional Partners:
NPC1
NPC intracellular cholesterol transporter 1.
   
 0.990
ENSTGUP00000018699
annotation not available
   
 0.904
ENSTGUP00000019011
annotation not available
   
 0.904
SCAP
Sterol regulatory element-binding protein cleavage-activating protein isoform X1.
   
 0.845
APOB
Apolipoprotein B.
     
 0.661
HACD3
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
      
 0.596
H0Z372_TAEGU
Uncharacterized protein.
     
 0.577
STARD3
StAR related lipid transfer domain containing 3.
      
 0.566
CHMP7
Charged multivesicular body protein 7.
      
 0.541
VIT2
Uncharacterized protein.
     
 0.530
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.