STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK3Janus kinase 3. (1113 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription.
   
 0.985
IFNGR2
Interferon gamma receptor 2 isoform X2.
   
 0.971
IFNGR1
Fibronectin type-III domain-containing protein.
   
 0.967
STAT1
Signal transducer and activator of transcription.
   
 0.958
STAT2
Signal transducer and activator of transcription 2.
   
 0.958
LOC115497673
Fibronectin type-III domain-containing protein.
   
 0.958
STAT4
Signal transducer and activator of transcription 4.
   
 0.956
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.949
SOCS3
Suppressor of cytokine signaling 3.
   
 0.874
SOCS1
Suppressor of cytokine signaling 1.
   
 0.853
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.