CCR5 protein (Taeniopygia guttata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CCR5

G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)

Predicted Functional Partners:

LOC100218724

0.967

CD4

0.943

CCL17

0.900

CX3CL1

0.841

CXCR4

0.818

CXCL12

0.791

CCL19

0.755

ARRB1

0.746

CCR7

0.734

LOC100229516

0.734

Your Current Organism:

Taeniopygia guttata

NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRB1	CCR5	ENSTGUP00000013972	ENSTGUP00000021568	Arrestin beta 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.746
ARRB1	CXCR4	ENSTGUP00000013972	ENSTGUP00000012180	Arrestin beta 1.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.784
ARRB1	LOC100218724	ENSTGUP00000013972	ENSTGUP00000031646	Arrestin beta 1.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.719
CCL17	CCR5	ENSTGUP00000037659	ENSTGUP00000021568	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.900
CCL17	LOC100218724	ENSTGUP00000037659	ENSTGUP00000031646	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.913
CCL19	CCR5	ENSTGUP00000030305	ENSTGUP00000021568	C-C motif chemokine ligand 19.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.755
CCL19	CCR7	ENSTGUP00000030305	ENSTGUP00000002421	C-C motif chemokine ligand 19.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.880
CCL19	CD4	ENSTGUP00000030305	ENSTGUP00000013698	C-C motif chemokine ligand 19.	Ig-like domain-containing protein.	0.420
CCL19	CX3CL1	ENSTGUP00000030305	ENSTGUP00000034344	C-C motif chemokine ligand 19.	Uncharacterized protein.	0.544
CCL19	CXCL12	ENSTGUP00000030305	ENSTGUP00000018339	C-C motif chemokine ligand 19.	Putative stromal cell derived factor 1; Belongs to the intercrine alpha (chemokine CxC) family.	0.863
CCL19	CXCR4	ENSTGUP00000030305	ENSTGUP00000012180	C-C motif chemokine ligand 19.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.735
CCL19	LOC100218724	ENSTGUP00000030305	ENSTGUP00000031646	C-C motif chemokine ligand 19.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.563
CCL19	LOC100229516	ENSTGUP00000030305	ENSTGUP00000020008	C-C motif chemokine ligand 19.	SCY domain-containing protein.	0.558
CCR5	ARRB1	ENSTGUP00000021568	ENSTGUP00000013972	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Arrestin beta 1.	0.746
CCR5	CCL17	ENSTGUP00000021568	ENSTGUP00000037659	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.900
CCR5	CCL19	ENSTGUP00000021568	ENSTGUP00000030305	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 19.	0.755
CCR5	CCR7	ENSTGUP00000021568	ENSTGUP00000002421	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.734
CCR5	CD4	ENSTGUP00000021568	ENSTGUP00000013698	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.943
CCR5	CX3CL1	ENSTGUP00000021568	ENSTGUP00000034344	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.841
CCR5	CXCL12	ENSTGUP00000021568	ENSTGUP00000018339	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Putative stromal cell derived factor 1; Belongs to the intercrine alpha (chemokine CxC) family.	0.791