STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRF2Uncharacterized protein. (1247 aa)    
Predicted Functional Partners:
RASGRF1
Ras protein specific guanine nucleotide releasing factor 1.
  
  
 
0.956
NRAS
NRAS proto-oncogene, GTPase.
    
 0.942
HRAS
Putative v-Ha-ras Harvey sarcoma viral oncogene variant 2.
    
 0.942
KRAS
GTPase KRas.
    
 0.942
MRAS
Muscle RAS oncogene homolog.
   
 0.941
RRAS2
RAS related 2.
   
 0.941
GRB2
Putative growth factor receptor-bound protein 2.
   
 0.903
CACNG3
Calcium voltage-gated channel auxiliary subunit gamma 3.
   
  0.666
CACNG5
Calcium voltage-gated channel auxiliary subunit gamma 5.
   
  0.666
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  0.663
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.