STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC115491434USP8_interact domain-containing protein. (317 aa)    
Predicted Functional Partners:
USP8
Uncharacterized protein; Belongs to the peptidase C19 family.
    
 0.953
SMURF1
E3 ubiquitin-protein ligase.
    
 0.911
SMURF2
E3 ubiquitin-protein ligase.
    
 0.911
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 0.911
NEDD4
E3 ubiquitin-protein ligase.
    
 0.911
ITCH
E3 ubiquitin-protein ligase.
    
 0.909
CBLB
Cbl proto-oncogene B.
    
 0.909
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
0.904
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
     
  0.900
EGFR
Receptor protein-tyrosine kinase.
    
 0.847
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.