STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLD4DNA polymerase delta subunit 4 isoform X1. (126 aa)    
Predicted Functional Partners:
POLD2
DNA polymerase delta 2, accessory subunit.
     
 0.982
POLD3
DNA polymerase delta 3, accessory subunit.
     
 0.787
ENSTGUP00000025959
annotation not available
    
 0.758
POLD1
DNA polymerase delta catalytic subunit.
    
 0.713
POLH
UmuC domain-containing protein.
     
 0.614
WRN
WRN RecQ like helicase.
     
 0.599
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
     
 0.597
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.589
POLA1
DNA polymerase.
    
 0.532
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.531
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.