STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)    
Predicted Functional Partners:
RAC2
Rac family small GTPase 2.
   
 0.963
RAC1
Rac family small GTPase 1.
   
 0.963
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 
 0.939
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 
0.935
LOC100221185
Uncharacterized protein.
    
 
0.935
PIK3R2
Uncharacterized protein.
    
 
0.935
PIK3CB
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 
 0.933
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 
 0.931
TIAM1
T cell lymphoma invasion and metastasis 1.
     
0.923
VAV3
Vav guanine nucleotide exchange factor 3.
  
  
 
0.901
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.