STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIGIRRSingle Ig and TIR domain containing. (504 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.796
IL18R1
TIR domain-containing protein.
   
 
0.617
TLR5
TIR domain-containing protein; Belongs to the Toll-like receptor family.
   
 0.596
IRAK2
Protein kinase domain-containing protein.
   
 0.522
RANBP2
RAN binding protein 2.
    
 0.521
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.519
TLR4
Toll like receptor 4; Belongs to the Toll-like receptor family.
    
 0.514
TOLLIP
Toll interacting protein.
      
 0.513
NLRC3
NLR family CARD domain containing 3.
   
 
 0.488
TRADD
TNFRSF1A associated via death domain.
    
 
 0.475
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.