STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP19Ubiquitin specific peptidase 19; Belongs to the peptidase C19 family. (1423 aa)    
Predicted Functional Partners:
RNF123
Ring finger protein 123.
   
 0.941
BIRC2
Uncharacterized protein.
    
 0.715
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 0.677
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.671
SIAH1
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
    
 
 0.670
SIAH2
E3 ubiquitin-protein ligase SIAH2.
    
 
 0.670
MYSM1
Uncharacterized protein.
   
 
 0.663
BIRC7
Baculoviral IAP repeat containing 7.
    
 0.655
NFKBIA
ANK_REP_REGION domain-containing protein.
    
 0.645
YARS1
Tyrosine--tRNA ligase.
      
 0.633
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.