STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORMDL1ORM1-like protein; Negative regulator of sphingolipid synthesis. (349 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
    
 
 0.884
SPTLC3
Aminotran_1_2 domain-containing protein.
    
 
 0.607
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
    
 
 0.607
ISM2
AMOP domain-containing protein.
    
 
 0.607
ISM1
Isthmin 1.
    
 
 0.607
ALAS1
5-aminolevulinate synthase.
    
 
 0.507
GCAT
Glycine C-acetyltransferase.
    
 
 0.507
ENSTGUP00000030322
annotation not available
    
 
 0.507
PMS1
PMS1 homolog 1, mismatch repair system component.
      
0.482
Your Current Organism:
Taeniopygia guttata
NCBI taxonomy Id: 59729
Other names: Poephila guttata, T. guttata, Taenopygia guttata, zebra finch
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.