node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOT13 | UBIAD1 | ENSTGUP00000032351 | ENSTGUP00000037680 | 4HBT domain-containing protein. | UbiA prenyltransferase domain containing 1. | 0.936 |
COQ2 | COQ5 | ENSTGUP00000002262 | ENSTGUP00000009866 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.737 |
COQ2 | DHDDS | ENSTGUP00000002262 | ENSTGUP00000001059 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.881 |
COQ2 | HAO1 | ENSTGUP00000002262 | ENSTGUP00000006600 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Hydroxyacid oxidase 1. | 0.830 |
COQ2 | HAO2 | ENSTGUP00000002262 | ENSTGUP00000027359 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. | 0.830 |
COQ2 | HMGCR | ENSTGUP00000002262 | ENSTGUP00000006291 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.697 |
COQ2 | IDI1 | ENSTGUP00000002262 | ENSTGUP00000020955 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Nudix hydrolase domain-containing protein. | 0.943 |
COQ2 | NUS1 | ENSTGUP00000002262 | ENSTGUP00000012256 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.881 |
COQ2 | UBIAD1 | ENSTGUP00000002262 | ENSTGUP00000037680 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | UbiA prenyltransferase domain containing 1. | 0.925 |
COQ5 | COQ2 | ENSTGUP00000009866 | ENSTGUP00000002262 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.737 |
COQ5 | UBIAD1 | ENSTGUP00000009866 | ENSTGUP00000037680 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | UbiA prenyltransferase domain containing 1. | 0.823 |
DHDDS | COQ2 | ENSTGUP00000001059 | ENSTGUP00000002262 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.881 |
DHDDS | HAO1 | ENSTGUP00000001059 | ENSTGUP00000006600 | Alkyl transferase; Belongs to the UPP synthase family. | Hydroxyacid oxidase 1. | 0.661 |
DHDDS | HAO2 | ENSTGUP00000001059 | ENSTGUP00000027359 | Alkyl transferase; Belongs to the UPP synthase family. | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. | 0.661 |
DHDDS | HMGCR | ENSTGUP00000001059 | ENSTGUP00000006291 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.540 |
DHDDS | IDI1 | ENSTGUP00000001059 | ENSTGUP00000020955 | Alkyl transferase; Belongs to the UPP synthase family. | Nudix hydrolase domain-containing protein. | 0.894 |
DHDDS | NUS1 | ENSTGUP00000001059 | ENSTGUP00000012256 | Alkyl transferase; Belongs to the UPP synthase family. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.998 |
DHDDS | UBIAD1 | ENSTGUP00000001059 | ENSTGUP00000037680 | Alkyl transferase; Belongs to the UPP synthase family. | UbiA prenyltransferase domain containing 1. | 0.846 |
HAO1 | COQ2 | ENSTGUP00000006600 | ENSTGUP00000002262 | Hydroxyacid oxidase 1. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.830 |
HAO1 | DHDDS | ENSTGUP00000006600 | ENSTGUP00000001059 | Hydroxyacid oxidase 1. | Alkyl transferase; Belongs to the UPP synthase family. | 0.661 |