STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIO31974.1Hypothetical protein. (499 aa)    
Predicted Functional Partners:
SIN83876.1
Signal transduction histidine kinase.
   
 0.863
SIN82477.1
PAS domain S-box-containing protein.
   
  0.798
SIO31984.1
Hypothetical protein.
       0.732
SIN82361.1
Signal transduction histidine kinase.
   
  0.580
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.526
SIN98826.1
Nicotinamide-nucleotide amidase; Belongs to the CinA family.
    
  0.513
SIN90677.1
Topoisomerase-4 subunit B.
   
 
 0.462
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.462
SIO31962.1
Lysozyme.
       0.458
SIN85969.1
Por secretion system C-terminal sorting domain-containing protein.
    
 
 0.420
Your Current Organism:
Chryseobacterium scophthalmum
NCBI taxonomy Id: 59733
Other names: ATCC 700039, C. scophthalmum, CCM 4109, CCUG 33454, CIP 104199, DSM 16779, Flavobacterium scophthalmum, LMG 13028, LMG:13028
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.