STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5WMT1_AGABUAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (484 aa)    
Predicted Functional Partners:
K5W3F1_AGABU
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 0.999
K5WSV7_AGABU
SAICAR_synt domain-containing protein.
  
 0.996
K5XL99_AGABU
ATP-grasp domain-containing protein.
  
 0.993
K5W6G1_AGABU
Amidophosphoribosyltransferase.
  
 
 0.988
K5WLE5_AGABU
ATP-grasp domain-containing protein.
  
 0.988
K5WXX4_AGABU
MGS domain-containing protein.
  
 0.987
K5Y2I5_AGABU
MGS domain-containing protein.
  
 0.987
K5Y5H2_AGABU
Formyl_trans_N domain-containing protein.
  
 0.980
K5X497_AGABU
ADK_lid domain-containing protein; Belongs to the adenylate kinase family.
   
 0.979
ADK1
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
   
 0.979
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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