STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5WPS4_AGABUGRIP domain-containing protein. (450 aa)    
Predicted Functional Partners:
K5WBA1_AGABU
Uncharacterized protein.
  
  
 0.901
URM1
Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]
    
 0.838
K5WZ78_AGABU
Uncharacterized protein.
    
 0.838
K5WU95_AGABU
Uncharacterized protein.
  
 
 0.817
K5WUW3_AGABU
Flavoprotein domain-containing protein.
  
 
 0.789
K5X5H1_AGABU
Thymidylat_synt domain-containing protein.
  
 
 0.789
K5W5A4_AGABU
Guanylate kinase-like domain-containing protein.
 
    
 0.773
K5XVK7_AGABU
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.759
K5XZ54_AGABU
CASP_C domain-containing protein.
    
 
 0.753
K5XQV2_AGABU
Tyrosine--tRNA ligase.
  
  
 0.714
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.