STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5WUT6_AGABUHelicase C-terminal domain-containing protein. (449 aa)    
Predicted Functional Partners:
K5X776_AGABU
Uncharacterized protein.
    
 0.944
K5X8I2_AGABU
WD_REPEATS_REGION domain-containing protein.
   
 0.867
K5XK15_AGABU
CBFD_NFYB_HMF domain-containing protein.
    
 0.850
K5X277_AGABU
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.826
K5XPF5_AGABU
Histone H2A; Belongs to the histone H2A family.
   
 0.765
K5W749_AGABU
Histone H2B; Belongs to the histone H2B family.
   
 0.744
K5WPY6_AGABU
Histone H2B; Belongs to the histone H2B family.
   
 0.744
K5Y4P7_AGABU
Uncharacterized protein.
   
 0.709
K5VUI9_AGABU
Uncharacterized protein.
   
 0.658
K5W9A0_AGABU
XPA_C domain-containing protein.
    
 0.655
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.