node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
K5W3F1_AGABU | K5W5A4_AGABU | K5W3F1 | K5W5A4 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Guanylate kinase-like domain-containing protein. | 0.548 |
K5W3F1_AGABU | K5W801_AGABU | K5W3F1 | K5W801 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Nucleoside diphosphate kinase. | 0.467 |
K5W3F1_AGABU | K5WHZ4_AGABU | K5W3F1 | K5WHZ4 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.994 |
K5W3F1_AGABU | K5WU95_AGABU | K5W3F1 | K5WU95 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.718 |
K5W3F1_AGABU | K5WWZ7_AGABU | K5W3F1 | K5WWZ7 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.968 |
K5W3F1_AGABU | K5WXX4_AGABU | K5W3F1 | K5WXX4 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | MGS domain-containing protein. | 0.981 |
K5W3F1_AGABU | K5WY31_AGABU | K5W3F1 | K5WY31 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GTP_cyclohydroI domain-containing protein. | 0.588 |
K5W3F1_AGABU | K5XJ37_AGABU | K5W3F1 | K5XJ37 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.487 |
K5W3F1_AGABU | K5Y2I5_AGABU | K5W3F1 | K5Y2I5 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | MGS domain-containing protein. | 0.981 |
K5W5A4_AGABU | K5W3F1_AGABU | K5W5A4 | K5W3F1 | Guanylate kinase-like domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.548 |
K5W5A4_AGABU | K5W801_AGABU | K5W5A4 | K5W801 | Guanylate kinase-like domain-containing protein. | Nucleoside diphosphate kinase. | 0.973 |
K5W5A4_AGABU | K5WHZ4_AGABU | K5W5A4 | K5WHZ4 | Guanylate kinase-like domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.605 |
K5W5A4_AGABU | K5WU95_AGABU | K5W5A4 | K5WU95 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein. | 0.985 |
K5W5A4_AGABU | K5WWZ7_AGABU | K5W5A4 | K5WWZ7 | Guanylate kinase-like domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.950 |
K5W5A4_AGABU | K5WY44_AGABU | K5W5A4 | K5WY44 | Guanylate kinase-like domain-containing protein. | dUTPase domain-containing protein. | 0.462 |
K5W5A4_AGABU | K5XJ37_AGABU | K5W5A4 | K5XJ37 | Guanylate kinase-like domain-containing protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.923 |
K5W801_AGABU | K5W3F1_AGABU | K5W801 | K5W3F1 | Nucleoside diphosphate kinase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.467 |
K5W801_AGABU | K5W5A4_AGABU | K5W801 | K5W5A4 | Nucleoside diphosphate kinase. | Guanylate kinase-like domain-containing protein. | 0.973 |
K5W801_AGABU | K5WHZ4_AGABU | K5W801 | K5WHZ4 | Nucleoside diphosphate kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.462 |
K5W801_AGABU | K5WU95_AGABU | K5W801 | K5WU95 | Nucleoside diphosphate kinase. | Uncharacterized protein. | 0.474 |