STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5WZX7_AGABUUncharacterized protein. (625 aa)    
Predicted Functional Partners:
K5XCG1_AGABU
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.908
K5VTZ8_AGABU
SAP domain-containing protein.
     
 0.833
K5Y5J8_AGABU
VWFA domain-containing protein.
    
 0.775
K5XNG8_AGABU
BRCT domain-containing protein.
    
 
 0.699
K5X1Z9_AGABU
DNA ligase; Belongs to the ATP-dependent DNA ligase family.
   
 
 0.695
K5WMD0_AGABU
zf-C2HE domain-containing protein.
    
 
 0.689
K5XHF4_AGABU
Uncharacterized protein.
    
 
 0.675
K5X6U2_AGABU
UmuC domain-containing protein.
   
  
 0.664
K5XH59_AGABU
Uncharacterized protein.
   
  
 0.664
K5VQK1_AGABU
Uncharacterized protein.
    
 
 0.662
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.