STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5X5W2_AGABUDNA_MISMATCH_REPAIR_2 domain-containing protein. (877 aa)    
Predicted Functional Partners:
K5XVQ3_AGABU
DNA_MISMATCH_REPAIR_2 domain-containing protein.
  
0.998
K5WWK1_AGABU
Uncharacterized protein.
 
 0.914
K5WYI6_AGABU
DNA_mis_repair domain-containing protein.
 
 0.913
K5VKH8_AGABU
Uncharacterized protein.
 
 0.900
K5WVQ4_AGABU
Uncharacterized protein.
  
 0.809
K5VQK1_AGABU
Uncharacterized protein.
   
 0.776
K5X1W1_AGABU
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.726
K5WXT1_AGABU
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.722
K5W6U8_AGABU
Uncharacterized protein.
    
 
 0.643
K5WJQ8_AGABU
Structural maintenance of chromosomes protein.
  
 
 0.639
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.