STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5XA62_AGABUHistidine biosynthesis trifunctional protein. (836 aa)    
Predicted Functional Partners:
K5WK60_AGABU
Aminotran_1_2 domain-containing protein.
 
 0.999
K5X7S1_AGABU
Uncharacterized protein.
 
 
 0.999
K5XY72_AGABU
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.
  
 
 0.999
K5Y5Y3_AGABU
Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.
 
 0.997
K5XHF4_AGABU
Uncharacterized protein.
  
 
 0.996
K5W6M1_AGABU
Tryptophan synthase.
  
  
 0.989
K5W3F1_AGABU
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
  
 0.978
K5X3I7_AGABU
N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.
  
  
 0.978
K5VPT1_AGABU
ACT domain-containing protein.
  
  
 0.977
K5WY30_AGABU
Uncharacterized protein.
  
 
 0.963
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.