K5XE46_AGABU protein (Agaricus bisporus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

K5XE46_AGABU

Uncharacterized protein. (597 aa)

Predicted Functional Partners:

K5XEX6_AGABU

0.511

BNA5

0.452

K5X1U0_AGABU

0.449

K5XBD8_AGABU

0.447

COQ5

0.446

K5WYG8_AGABU

0.431

COQ3

0.408

K5W8I2_AGABU

0.408

K5WZG9_AGABU

0.408

K5X5M8_AGABU

0.408

Your Current Organism:

Agaricus bisporus

NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BNA5	K5XE46_AGABU	K5W7D8	K5XE46	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	Uncharacterized protein.	0.452
COQ3	COQ5	K5W4P5	K5XW23	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.589
COQ3	K5XBD8_AGABU	K5W4P5	K5XBD8	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.410
COQ3	K5XE46_AGABU	K5W4P5	K5XE46	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.408
COQ5	COQ3	K5XW23	K5W4P5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.589
COQ5	K5W8I2_AGABU	K5XW23	K5W8I2	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Methyltransf_25 domain-containing protein.	0.440
COQ5	K5WZG9_AGABU	K5XW23	K5WZG9	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.589
COQ5	K5X5M8_AGABU	K5XW23	K5X5M8	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.440
COQ5	K5XBD8_AGABU	K5XW23	K5XBD8	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.675
COQ5	K5XE46_AGABU	K5XW23	K5XE46	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Uncharacterized protein.	0.446
K5W8I2_AGABU	COQ5	K5W8I2	K5XW23	Methyltransf_25 domain-containing protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.440
K5W8I2_AGABU	K5XBD8_AGABU	K5W8I2	K5XBD8	Methyltransf_25 domain-containing protein.	Uncharacterized protein.	0.410
K5W8I2_AGABU	K5XE46_AGABU	K5W8I2	K5XE46	Methyltransf_25 domain-containing protein.	Uncharacterized protein.	0.408
K5WYG8_AGABU	K5X1U0_AGABU	K5WYG8	K5X1U0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.999
K5WYG8_AGABU	K5XE46_AGABU	K5WYG8	K5XE46	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Uncharacterized protein.	0.431
K5WYG8_AGABU	K5XEX6_AGABU	K5WYG8	K5XEX6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.688
K5WZG9_AGABU	COQ5	K5WZG9	K5XW23	Uncharacterized protein.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.589
K5WZG9_AGABU	K5XBD8_AGABU	K5WZG9	K5XBD8	Uncharacterized protein.	Uncharacterized protein.	0.410
K5WZG9_AGABU	K5XE46_AGABU	K5WZG9	K5XE46	Uncharacterized protein.	Uncharacterized protein.	0.408
K5X1U0_AGABU	K5WYG8_AGABU	K5X1U0	K5WYG8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.999