STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5XIT4_AGABUUncharacterized protein. (333 aa)    
Predicted Functional Partners:
K5X429_AGABU
Aminotran_5 domain-containing protein.
  
 0.980
UBA4
Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subseque [...]
   
 0.976
K5Y441_AGABU
Aspartate aminotransferase.
  
 
 0.970
K5Y6M5_AGABU
Aspartate aminotransferase.
  
 
 0.970
K5X4R6_AGABU
Uncharacterized protein.
    
 0.965
K5XEX9_AGABU
Flavodoxin-like domain-containing protein.
    
 0.965
K5X162_AGABU
Uncharacterized protein.
  
 
 0.962
K5W6G4_AGABU
Thioredoxin domain-containing protein.
    
 0.936
K5VZK1_AGABU
PAPS_reduct domain-containing protein.
    
 0.932
K5W084_AGABU
FAD-binding FR-type domain-containing protein.
    
 0.922
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.