STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
K5Y6U7_AGABUCS domain-containing protein. (190 aa)    
Predicted Functional Partners:
K5XS34_AGABU
Serine/threonine-protein kinase.
   
 0.953
PAC1
Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family.
   
 0.922
K5Y6I5_AGABU
NUDE_C domain-containing protein.
     
 0.872
K5W4W7_AGABU
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
   
 
 0.799
K5XX93_AGABU
Uncharacterized protein.
    
 0.773
K5XZK7_AGABU
TOG domain-containing protein.
     
 0.751
K5XB19_AGABU
Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
     
 0.728
K5XIA3_AGABU
Importin N-terminal domain-containing protein.
   
 
  0.728
K5X6D6_AGABU
Uncharacterized protein.
   
 
 0.720
K5X7R7_AGABU
Uncharacterized protein.
   
 
  0.716
Your Current Organism:
Agaricus bisporus
NCBI taxonomy Id: 597362
Other names: A. bisporus var. burnettii JB137-S8, Agaricus bisporus var. burnettii JB137-S8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.