node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fen1 | WH47_00089 | A0A0L7R2F5 | A0A0L7RK58 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit gamma-1, mitochondrial. | 0.702 |
Fen1 | WH47_07498 | A0A0L7R2F5 | A0A0L7RFZ4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Fanconi anemia group D2 protein. | 0.432 |
Fen1 | WH47_08263 | A0A0L7R2F5 | A0A0L7RG99 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Double-strand break repair protein MRE11; Belongs to the universal ribosomal protein uS11 family. | 0.988 |
Fen1 | WH47_10815 | A0A0L7R2F5 | A0A0L7RCW0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Triosephosphate isomerase. | 0.460 |
Fen1 | WH47_11058 | A0A0L7R2F5 | A0A0L7QLK4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ribonuclease H1. | 0.827 |
Fen1 | WH47_12101 | A0A0L7R2F5 | A0A0L7R1C0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein RAD50. | 0.940 |
WH47_00089 | Fen1 | A0A0L7RK58 | A0A0L7R2F5 | DNA polymerase subunit gamma-1, mitochondrial. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.702 |
WH47_00089 | WH47_00418 | A0A0L7RK58 | A0A0L7R774 | DNA polymerase subunit gamma-1, mitochondrial. | Single-stranded DNA-binding protein, mitochondrial. | 0.698 |
WH47_00089 | WH47_05096 | A0A0L7RK58 | A0A0L7QS76 | DNA polymerase subunit gamma-1, mitochondrial. | Twinkle protein, mitochondrial. | 0.816 |
WH47_00089 | WH47_06628 | A0A0L7RK58 | A0A0L7QRI6 | DNA polymerase subunit gamma-1, mitochondrial. | DNA polymerase subunit gamma-2, mitochondrial. | 0.769 |
WH47_00089 | WH47_07498 | A0A0L7RK58 | A0A0L7RFZ4 | DNA polymerase subunit gamma-1, mitochondrial. | Fanconi anemia group D2 protein. | 0.780 |
WH47_00089 | WH47_08263 | A0A0L7RK58 | A0A0L7RG99 | DNA polymerase subunit gamma-1, mitochondrial. | Double-strand break repair protein MRE11; Belongs to the universal ribosomal protein uS11 family. | 0.747 |
WH47_00089 | WH47_10815 | A0A0L7RK58 | A0A0L7RCW0 | DNA polymerase subunit gamma-1, mitochondrial. | Triosephosphate isomerase. | 0.665 |
WH47_00089 | WH47_11058 | A0A0L7RK58 | A0A0L7QLK4 | DNA polymerase subunit gamma-1, mitochondrial. | Ribonuclease H1. | 0.751 |
WH47_00089 | WH47_11209 | A0A0L7RK58 | A0A0L7QKH3 | DNA polymerase subunit gamma-1, mitochondrial. | Fanconi anemia group I protein like protein. | 0.671 |
WH47_00089 | WH47_12101 | A0A0L7RK58 | A0A0L7R1C0 | DNA polymerase subunit gamma-1, mitochondrial. | DNA repair protein RAD50. | 0.688 |
WH47_00418 | WH47_00089 | A0A0L7R774 | A0A0L7RK58 | Single-stranded DNA-binding protein, mitochondrial. | DNA polymerase subunit gamma-1, mitochondrial. | 0.698 |
WH47_00418 | WH47_05096 | A0A0L7R774 | A0A0L7QS76 | Single-stranded DNA-binding protein, mitochondrial. | Twinkle protein, mitochondrial. | 0.593 |
WH47_00418 | WH47_06628 | A0A0L7R774 | A0A0L7QRI6 | Single-stranded DNA-binding protein, mitochondrial. | DNA polymerase subunit gamma-2, mitochondrial. | 0.515 |
WH47_00418 | WH47_08263 | A0A0L7R774 | A0A0L7RG99 | Single-stranded DNA-binding protein, mitochondrial. | Double-strand break repair protein MRE11; Belongs to the universal ribosomal protein uS11 family. | 0.543 |