node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ORX09152.1 | ORX14529.1 | AWC31_09355 | AWC31_25390 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
ORX09152.1 | hisB | AWC31_09355 | AWC31_28780 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
ORX09152.1 | hisC | AWC31_09355 | AWC31_28785 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.981 |
ORX09152.1 | hisD | AWC31_09355 | AWC31_28790 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.602 |
ORX09152.1 | hisF | AWC31_09355 | AWC31_28760 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.985 |
ORX09152.1 | hisG | AWC31_09355 | AWC31_08055 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | 0.980 |
ORX09152.1 | hisH | AWC31_09355 | AWC31_28775 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.970 |
ORX09152.1 | hisI | AWC31_09355 | AWC31_28755 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.981 |
ORX09152.1 | priA | AWC31_09355 | AWC31_28770 | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. | 0.983 |
ORX14529.1 | ORX09152.1 | AWC31_25390 | AWC31_09355 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
ORX14529.1 | hisB | AWC31_25390 | AWC31_28780 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |
ORX14529.1 | hisC | AWC31_25390 | AWC31_28785 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.947 |
ORX14529.1 | hisD | AWC31_25390 | AWC31_28790 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.947 |
ORX14529.1 | hisF | AWC31_25390 | AWC31_28760 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.611 |
ORX14529.1 | hisG | AWC31_25390 | AWC31_08055 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. | 0.532 |
ORX14529.1 | hisH | AWC31_25390 | AWC31_28775 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.438 |
ORX14529.1 | hisI | AWC31_25390 | AWC31_28755 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.459 |
ORX14529.1 | priA | AWC31_25390 | AWC31_28770 | Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. | 0.630 |
ORX17743.1 | hisB | AWC31_14995 | AWC31_28780 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.469 |
ORX17743.1 | hisC | AWC31_14995 | AWC31_28785 | Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.955 |